World Journal of Gastroenterology, Vol. 12(22) pp. 3616-3619. June 2006
Noni juice is not hepatotoxic.
B. J. West, C. J. Jensen, J. Westendorf

Noni juice has been approved as a safe food within the European Union. A few cases reports suggesting a role of noni juicein acute hepatitis, due to anthraquinones, is not supported by chemical analyses, several preclinical safety studies, and a clinical human safety study in 96 volunteers. Liver function tests in these studies revealed no adverse liver effects, even at very high doses. Anthraquinones in noni fruit are of the wrong type and occur in quantities too small to cause any negative liver effects. A large amount of data reveal that noni juice is not hepatotoxic. (original article available at )