Int J Biol Macromol. 2017 Oct;103:1121-1129.
Morinda citrifolia lipid transfer protein 1 exhibits anti-inflammatory activity by modulation of pro- and anti-inflammatory cytokines.
Campos DCO, Costa AS, Luz PB, Soares PMG, Alencar NMN, Oliveira HD.
Ingestion of a thermostable lipid transfer protein isolated from noni seeds inhibited cell migration in carrageenan-induced peritonitis and mouse paw edema induced by carrageenan and dextran. The lipid transfer protein also inhibited the production of cytokines IL-1β, IL-6, and TNF-α and increased production of the anti-inflammatory cytokine IL-10. It also reduced pancreatic injury and the activities of amylase, lipase, and pancreatitis-associated lung injury. (original abstract available at https://www.ncbi.nlm.nih.gov/pubmed/28559184).